Movie 5.
Live-cell imaging of a COS-7 cell expressing I1061T mutant NPC1-EGFP (white), demonstrating a loss of LE/L motility and tubulation. Mag. bar = 5 μm and time stamp is mins:secs:millisecs.
StARD9 is a novel lysosomal kinesin required for membrane tubulation, cholesterol transport and Purkinje cell survival
J Cell Sci 2023. 136:None-None; doi: 10.1242/jcs.260662