Movie 3.
RGC growth cone expressing mNG-TOCA-1-W517K and GAP43-RFP, showing more diffuse TOCA-1 puncta with reduced enrichment of TOCA-1 to filopodia. 3 minute video acquired at 1.5 s per frame, replayed at 20 frames per second.
Filopodial protrusion driven by density-dependent Ena–TOCA-1 interactions
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261057