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Movie 6.

Decreasing integrin protein levels reduces actin accumulation at the wound edge. Wound healing in embryos expressing wild-type mys (control, left) or the temperature-sensitive allele mysts1 (right). Embryos also expressed UtrophinABD:GFP and were exposed to the restrictive temperature. Images were acquired every 30 s. Time after wounding is shown. Anterior left, dorsal up. Bar, 10 μm.

Integrin-based adhesions promote cell–cell junction and cytoskeletal remodelling to drive embryonic wound healing

Michelle Ly, Clara Schimmer, Raymond Hawkins, Katheryn E. Rothenberg, and Rodrigo Fernandez-Gonzalez

J Cell Sci 2023. 137:None-None; doi: 10.1242/jcs.261138