Mute
Current Time 0:00
/
Duration Time 0:00
Loaded: 0%
Progress: 0%
Stream TypeLIVE
Remaining Time -0:00
 

Movie 1.

FRAP of Fat2-3xGFP, Lar-3xGFP, and Sema5c-3xGFP at interfaces in control and fat2N103-2 epithelia. Movies begin 20 seconds before photobleaching and follow leading-trailing interfaces (control) or similarly-oriented interfaces (fat2N103-2) for the subsequent 8 minutes. Display brightness settings are adjusted separately for each fluorophore, but preserved between control and fat2N103-2 conditions. Associated with Figs. 6B,D; S3A-F.

Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells

Audrey Miller Williams, and Sally Horne-Badovinac

J Cell Sci 2023. 137:None-None; doi: 10.1242/jcs.261173