Movie 1.

Live-cell imaging at 300 ms of NPY pHTomato exocytosis in untreated PC12 (Left) and Thapsigargin (Tg) treated PC12 cells (Right), showing a significant reduction in Dense Core Vesicle (DCV) release in stressed cells.

Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches

Mohima Mukherjee, Chandramouli Mukherjee, Vinayak Ghosh, Aamna Jain, Souren Sadhukhan, Sushma Dagar, and Bhavani Shankar Sahu

J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261257