Movie 9.
Live-cell imaging at 300 ms of NPY pHluorin exocytosis in untreated INS-1 (Left) and Thapsigargin (Tg) treated INS-1 cells (Right), showing significant reduction in Dense Core Vesicle (DCV) release in stressed cells.
Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261257