Movie 2.
Imaging of microtubules growing in EB1-EGFP-expressing CTLs, pre-treated with 100 nM BI2536 for 3 h and plated on anti-CD3/CD28-coated glass-bottom chambers. Images were taken for 3 minutes using a TIRF microscope.
Polo-like kinase 1 regulates immune synapse assembly and cytotoxic T cell function by driving microtubule dynamics
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261476