Movie 11.

External forces induce GFP-S100A11 accumulation at stressed FAs. Pulling forces are applied to a single U2OS cell expressing GFP-S100A11 via a glass micropipette.

S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry

Tareg Omer Mohammed, You-Rong Lin, Lucky Akter, Kai Weissenbruch, Kien Xuan Ngo, Yanjun Zhang, Noriyuki Kodera, Martin Bastmeyer, Yusuke Miyanari, Azuma Taoka, and Clemens M. Franz

J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261492