Movie 7.
Ionomycin induced cell contraction is blocked by NMII inhibition. U2OS cells stimulated with 3 μM ionomycin either without (left) or with (right) blebbistatin preincubation (50 μM) were imaged by holographic tomography. Without blebbistatin, ionomycin induces cell contraction and membrane bleb formation.
S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261492