Movie 10.

Dynamic microtubule polymerizing against a branched actin meshwork in presence of 100nM of Tau. Time-lapse imaging of dynamic microtubules (green) polymerizing against a branched actin network (magenta) in presence of actin bundles (10nM of Arp2/3 complex) and of an actin-microtubule crosslinker (100nM of Tau). White arrows show microtubule + tip piercing the branched actin meshwork. Scale bar, 10 µm.

Microtubules under mechanical pressure can breach dense actin networks

Matthieu Gélin, Alexandre Schaeffer, Jérémie Gaillard, Christophe Guérin, Benoit Vianay, Magali Orhant-Prioux, Marcus Braun, Christophe Leterrier, Laurent Blanchoin, and Manuel Théry

J Cell Sci 2023. 136:None-None; doi: 10.1242/jcs.261667