Movie 4.
Thrombin restores cell adhesion in DLC1-overexpressing HUVECs. Live TIRF microscopy recordings of imaged HUVECs transduced with GFP (Control), GFP-DLC1 or GFP-DLC1-R677E and mCherry-paxillin stimulated with thrombin.
DLC1 promotes mechanotransductive feedback for YAP via RhoGAP-mediated focal adhesion turnover
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261687