Movie 2.
Time-lapse imaging of Coilin-mRuby2 during Cajal body reformation that was transiently expressed in HeLa cells. Images were acquired every 2 min for 3 hrs after washout of harmine. After 30 min of recovery culture, Coilin reforms Cajal bodies simultaneously with the disappearance from PNC.
Dissecting the role of SMN multimerization in its dissociation from the Cajal body using harmine as a tool compound
J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.261834