Movie 3.

Constitutively active c-Src reduces cell migration in 2D. Corresponds to Supplementary Fig. 4A. HUVECs transduced with mScarlet-tagged c-Src mutants migrating in a scratch assay for live imaging of mScarlet (black) at 10 min interval over 15 h.

c-Src-induced vascular malformations require localised matrix degradation at focal adhesions

Patricia Essebier, Mikaela Keyser, Teodor Yordanov, Brittany Hill, Alexander Yu, Ivar Noordstra, Alpha S. Yap, Samantha J. Stehbens, Anne K. Lagendijk, Lilian Schimmel, and Emma J. Gordon

J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.262101

Download Original Video