Movie 4.

R848-protocell treatment increases macrophage velocity at the wound site. Time-lapse confocal movies showing tracks of macrophage nuclei (green) at the wound site in wounded Tg(mpeg1:FRET) larvae at 48 hours post-wounding after each protocell treatment. Note that warm and cold track colours indicate faster and slower macrophage velocity, respectively.

Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing

Paco López-Cuevas, Tiah C. L. Oates, Qiao Tong, Lucy M. McGowan, Stephen J. Cross, Can Xu, Yu Zhao, Zhuping Yin, Ashley M. Toye, Asme Boussahel, Chrissy L. Hammond, Stephen Mann, and Paul Martin

J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.262202