Movie 6.

R848-protocell treatment increases bacterial uptake by macrophages. Time-lapse Incucyte movies of zoomed-in regions from wells containing cultured human macrophages incubated with bacterial bioparticles (red) after each protocell treatment. Note that white outlines indicate detected macrophages and white numbers indicate the order of appearance for detected macrophages.

Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing

Paco López-Cuevas, Tiah C. L. Oates, Qiao Tong, Lucy M. McGowan, Stephen J. Cross, Can Xu, Yu Zhao, Zhuping Yin, Ashley M. Toye, Asme Boussahel, Chrissy L. Hammond, Stephen Mann, and Paul Martin

J Cell Sci 2024. 137:None-None; doi: 10.1242/jcs.262202