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Movie 1.

NPM1 wild-type nucleoli rim localisation in living cells. HeLa cells were transfected with Scar_NPM1_wt (Red) construct and counterstained with SiR-DNA (Grey) before live imaging. Movie shown is of the same cell imaged every 15 mins over a period 6 hrs.

Abnormal nucleoli architecture and aggregate formation in nucleophosmin mutated acute myeloid leukaemia

Martin Grundy, Kellie Lucken, Xiaomeng Xing, Eva L. Simpson, Alice Worker, Ahmed Bayyoomi, Alison J. Beckett, Ian A. Prior, Daniel G. Booth, and Claire H. Seedhouse

J Cell Sci 2025. 138:None-None; doi: 10.1242/jcs.263553