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Movie 5.

Dynamic association of RFFL vesicles with mitochondria and MFN2. Confocal time-lapse imaging of A549 cells stably expressing RFFL-EGFP (Green), transfected with MFN2-iRFP670 (Red) and stained for mitochondria with MitoTracker Red CMXRos (Blue) (10 frames per second). Related to Fig. 2D.

Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2

Nikhil Dev Narendradev, Rishith Ravindran, Parul Jain, Shikha Chaudhary, Anoop Kumar G. Velikkakath, Abyasree Sudharman, Adithya Janardhanan, Tapas Chandra Nag, Subhash Chandra Yadav, and Srinivasa Murty Srinivasula

J Cell Sci 2025. 138:None-None; doi: 10.1242/jcs.263830