Movie 3

Examplifying videos #1-3 of tangled RBCs in the chicken chorioallantoic membrane (CAM) at d10. At day 10 after incubation (d10), the chick CAM contains high numbers of capillary beds. In these regions, dumbbell-shaped RBCs tangle up at vascular structures.

Splitting of circulating red blood cells as an in vivo mechanism of erythrocyte maturation in developing zebrafish, chick and mouse embryos

Daniel Brönnimann, Tiziana Annese, Thomas A. Gorr, and Valentin Djonov

Journal of Experimental Biology 2018. 221:None-None; doi: 10.1242/jeb.184564