To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 1 A control trial (control 1) where no active torque is produced at the ankle or TMT (plantaris muscle is absent. In vitro virtual reality: an anatomically explicit musculoskeletal simulation powered by in vitro muscle using closed-loop tissue–software interaction Christopher T. Richards, and Enrico A. Eberhard Journal of Experimental Biology 2020. 223:None-None; doi: 10.1242/jeb.210054 Download Original Video