Movie 2.
hb RNAi simulation. In silico knockdown of hb. hb expression is absent, and later cascade genes (Kr, mlpt, and gt) fail to initiate in the posterior. svb is still activated in the posterior, but without mlpt or gt activity it neither propagates anteriorly nor clears posteriorly, leaving it restricted to the posterior growth zone.
Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization
Biology Open 2026. 15:None-None; doi: 10.1242/bio.062391