Movie 3.
Kr RNAi simulation. In silico knockdown of Kr. hb expands anteriorly due to loss of repression. mlpt and gt fail to initiate. svb is activated in the posterior but cannot propagate anteriorly without mlpt, and also fails to clear posteriorly without gt, resulting in a persistent posterior cap.
Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization
Biology Open 2026. 15:None-None; doi: 10.1242/bio.062391