Movie 4.

mlpt RNAi simulation. In silico knockdown of mlpt. Kr extends posteriorly, while gt fails to initiate. svb is activated in the posterior but fails to propagate anteriorly, demonstrating that its anterior spread depends on mlpt.

Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization

Mahla Ahmadi, Heike Rudolf, Christine Mau, Jimena Garcia-Guillen, and Ezzat El-Sherif

Biology Open 2026. 15:None-None; doi: 10.1242/bio.062391