Movie 5.

svb RNAi simulation. In silico knockdown of svb. gt fails to activate, reflecting the requirement of the Mlpt-Svb complex for gt expression, and mlpt expression expands due to the absence of repression by gt.

Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization

Mahla Ahmadi, Heike Rudolf, Christine Mau, Jimena Garcia-Guillen, and Ezzat El-Sherif

Biology Open 2026. 15:None-None; doi: 10.1242/bio.062391