Movie 7

Dorsal closure defect after Tc-Doc^RNAi. The transgenic nuclear-GFP embryo is shown in dorsal aspect with anterior left. Extraembryonic membrane rupture and dorsal organ formation are morphologically wild type, but dorsal closure does not proceed in the posterior third of the embryo and finally the flanks of the embryo rip open again. Image stacks were acquired every 10 min at 24°C and are shown as maximum intensity projections at each time point. See also main text Figure 7.