Movie 4.
hoxb7a-overexpressing cells transplanted to the lateral germ ring margin exhibited delayed ingression compared with those of control. Time-lapse fluorescence movie visualizing cell ingression of control (green) and hoxb7a-overexpressing (magenta) cells transplanted to the lateral germ ring margin at the 40% epiboly stage. Imaging was started at the 50% epiboly stage (lateral view). Cell membranes of host embryo were labelled by injection of memRFP mRNA. Time interval, 4 min 43 sec. Duration, 3 hours 18 min. Scale bar, 100 μm.
Hoxb genes determine the timing of cell ingression by regulating cell surface fluctuations during zebrafish gastrulation
Development 2025. 152:None-None; doi: 10.1242/dev.204261