Movie 5.
Transplanted control cells entered a frequent blebbing state, whereas cotransplanted hoxb1b morphant cells did not and instead exhibited a static state. Timelapse fluorescence movie visualizing cell blebbing behavior of control (green) and hoxb1b morphant (magenta) cells transplanted to the lateral germ ring margin at the 40% epiboly stage. Imaging was started at the 50% epiboly stage (lateral view). Time interval, 30 sec. Duration, 20 min. Scale bar, 60 μm.
Hoxb genes determine the timing of cell ingression by regulating cell surface fluctuations during zebrafish gastrulation
Development 2025. 152:None-None; doi: 10.1242/dev.204261