Movie 9.

caRhoA-overexpressing hoxb1b morphant cells exhibited a rescued phenotype characterized by the timing of entry into a frequent blebbing state. Timelapse fluorescence movie visualizing cell blebbing behavior of control (green) and caRhoAinjected hoxb1b morphant (magenta) cells transplanted to the lateral germ ring margin at the 40% epiboly stage. Imaging was started at the 50% epiboly stage (lateral view). Time interval, 30 sec. Duration, 20 min. Scale bar, 60 μm.

Hoxb genes determine the timing of cell ingression by regulating cell surface fluctuations during zebrafish gastrulation

Yuuta Moriyama, Toshiyuki Mitsui, and Carl-Philipp Heisenberg

Development 2025. 152:None-None; doi: 10.1242/dev.204261