Movie 2.
pHes7-Achilles reporter activity in WT (left) and Cdh2-KO (right) iPSMs, related to Fig. 1. The experimental setup is equivalent to Movie 1. N=3 independent experiments (rounds of differentiation and live imaging) and n=3 biological replicates (cell lines) for each experiment. Scale bar = 100μm.
Cdh2, a downstream target of Hes7, regulates somitogenesis by supporting FGF signalling
Development 2025. 152:None-None; doi: 10.1242/dev.204743