Movie 1.
Cranial EC1.45 activity at 2 dpf, focusing on jaw-adjacent signal. Animated movie of a confocal z-stack in 3D illustrating the location of eGFP-positive cells (EC1.45-activity) in relation to mRFP (developing jaw precartilaginous condensations) at 2 dpf for a cross between the transgenic lines Tg(HuP1P2:GFP) and Tg(sox10:mRFP). Prepared in Imaris, scale bar is indicated.
Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development
Development 2025. 152:None-None; doi: 10.1242/dev.204779