Movie 1.

Cranial EC1.45 activity at 2 dpf, focusing on jaw-adjacent signal. Animated movie of a confocal z-stack in 3D illustrating the location of eGFP-positive cells (EC1.45-activity) in relation to mRFP (developing jaw precartilaginous condensations) at 2 dpf for a cross between the transgenic lines Tg(HuP1P2:GFP) and Tg(sox10:mRFP). Prepared in Imaris, scale bar is indicated.

Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development

Kirsty Uttley, Hannah J. Jüllig, Carlo De Angelis, Julia M. T. Auer, Ewa Ozga, Hemant Bengani, and Hannah K. Long

Development 2025. 152:None-None; doi: 10.1242/dev.204779