Movie 3.

Dinaciclib treatment inhibits ectoderm divisions and prevents ME boundary refinement. Mesectoderm (centre) and ectoderm (top and bottom) cells in embryos expressing Ecadherin: GFP, and injected, 1 hour after the onset of mesectoderm divisions, with 50% DMSO (left) or 500 μM dinaciclib (right). Anterior, left. Images were acquired every 30 seconds.

Cell divisions both challenge and refine tissue boundaries in the Drosophila embryo

Veronica Castle, Merdeka Miles, Rafael Perez-Vicente, Rodrigo Fernandez-Gonzalez, and Gonca Erdemci-Tandogan

Development 2026. 153:None-None; doi: 10.1242/dev.204817