Movie 1.
BLECs in a control-injected brain. 3D animation followed by single planes from dorsal to ventral of light sheet microscopy images of a mrc1a:mCitrine-positive, cleared control brain showing BLECs by immunostaining against GFP. BLECs populate the leptomeninges. Note that the dorsal forebrain is devoid of BLECs.
Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function
Development 2026. 153:None-None; doi: 10.1242/dev.204988