Movie 1
‘Swimming’ or ‘waddling‘ gait of tg TDP-43A315T mouse on a high-fat diet nearing end stage. This movie shows the characteristic abnormal walk of a tg TDP-43A315T mouse sustained on a high-fat jelly diet experiencing a ‘swimming’ or ‘waddling’ gait later in disease progression.
A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice
Disease Models and Mechanisms 2016. 9:1029-1037; doi: 10.1242/dmm.024786