Movie 4.

Pulsatile recruitment of PHAkt-eGFP to a neutrophil phagosome containing 1μm latex beads (blue spheres). 1μm bead is within the neutrophil at the start of the movie. PHAkt-eGFP recruits to the phagosome membrane (3m 5s) (Pulse). PHAkt-eGFP then dissipates from the phagosome membrane (8m 34). Green = PHAkt-eGFP. 1μm latex beads (blue spheres).

A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity

Clare F. Muir, Constantino Carlos Reyes-Aldasoro, Tomasz K. Prajsnar, Bartosz J. Michno, Justyna Cholewa-Waclaw, Yin X. Ho, Audrey Bernut, Catherine A. Loynes, Stone Elworthy, Kieran A. Bowden, Ashley J. Cadby, Lynne R. Prince, Jason S. King, Felix Ellett, Alison M. Condliffe, and Stephen A. Renshaw

Disease Models and Mechanisms 2025. 18:None-None; doi: 10.1242/dmm.052042

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