To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 1 PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA A. P. Struckhoff, M. K. Rana, S. S. Kher, M. E. Burow, J. L. Hagan, L. Del Valle, and R. A. Worthylake J Cell Sci 2013. 126:4514-4526; doi: 10.1242/jcs.132381 Download Original Video