Movie 14
Live imaging video file (Movie 14) and serial tomogram and 3D model (Movie 15) corresponding to Fig 4A and Fig. 4E, respectively. Tomograms of twenty consecutive 300nm sections were acquired at 9400X magnification and later aligned. Movie 15 shows a central double-membrane autophagosome containing several vesicles.
Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells
J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.226241