Movie 5 (related to Figure 3J)
MNT-1 cells were co-transfected with LAMP1-mRuby2 and 2xFYVE-GFP and treated for 2 h with 1.6 μM YM201636. Movie shows magnification of boxed region in Figure 5B. The movie was taken at 0.4 sec frame rate and 30 frames are shown.
The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation
J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.229500