Movie 3. Ezrin cleavage in the extending pseudopodia during phagocytosis
The movie, from which fig 8 was constructed, shows an enlarged view of a RAW 264.7 cell expressing both ezrin-GFPi and ezrin-mCherry extending pseudopodia to engulf an C3bi-opsonised zymosan particle. The sequence is pseudo-coloured, according the colour bar shown at the start of the sequence, and shows the dynamic changes in GFP/mCherry ratio during phagocytosis.
Ca2+-activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion
J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.236968