Mute
Current Time 0:00
/
Duration Time 0:00
Loaded: 0%
Progress: 0%
Stream TypeLIVE
Remaining Time -0:00
 

Movie 3.

Live-cell time-lapse imaging of Lifeact-ruby (gray) to visualize Factin and mucins (red) during exocytosis in Rab1-RNAi-expressing cells shows that small granules undergo exocytosis. Arrow points to a granule undergoing exocytosis. Movie shows a single slice from a z-stack comprising 13 optical slices at a 1.0 μm step size. A total of 200 frames were captured, comprising ∼15 mins total time. Movie shows 69 frames comprising a total of ∼5.4 mins total time. Full genotype: UAS-lifeact-ruby/UAS-Rab1-RNAi; Sgs3>/Sgs3-GFP.

A novel function for Rab1 and Rab11 during secretory granule maturation

Sarah D. Neuman, Annika R. Lee, Jane E. Selegue, Amy T. Cavanagh, and Arash Bashirullah

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.259037