Movie 1.
Focal adhesion turnover of control and Cyri-b KO cells. Live imaging of B16-F1 control and Cyri-b KO cells expressing pEGFP-Paxillin. 1 image acquired every minute for 30 minutes to analyse focal adhesion dynamics. Playback rate at 5 frames per second. Scale bar 25 μm.
CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
J Cell Sci 2025. 138:None-None; doi: 10.1242/jcs.263646