Movie 4.

EB1 growth rates. EB1 growth rates measured using pGFP-EB1 in B16-F1 control and Cyri-b KO cells with inhibitors (LatruculinA or Blebbistatin). 1 image per second for 120 seconds and playback at 10 frames per second. Scale bar represents 25 μm.

CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge

Jamie A. Whitelaw, Sayantika Ghosh, Sergio Lilla, Savvas Nikolaou, Luke Tweedy, Loic Fort, Nikki R. Paul, Sara Zanivan, Nikolaj Gadegaard, Robert H. Insall, and Laura M. Machesky

J Cell Sci 2025. 138:None-None; doi: 10.1242/jcs.263646