Movie 1.
The proposed movements and interactions of macropinosomes and lysosomes. After formation at the plasma membrane (left side), macropinosomes interact transiently with other macropinosomes and lysosomes, eventually merging into lysosomes (right-most organelle).
Macropinocytosis facilitates amino acid acquisition from extracellular fluid to support cell proliferation in macrophages
J Cell Sci 2026. 139:None-None; doi: 10.1242/jcs.264398