Movie 2.
The diffusion and flow of solutes enclosed into a macropinosome. The macropinosome interacts with other macropinosomes before fusion with the lysosome. Small solutes (dots) can exchange with other organelles more readily than can larger solutes (red dots in circles).
Macropinocytosis facilitates amino acid acquisition from extracellular fluid to support cell proliferation in macrophages
J Cell Sci 2026. 139:None-None; doi: 10.1242/jcs.264398