Movie 1.

Obtustatin inhibits elongation of nascent BC. Time-lapse (5 fps) of control and obtust-treated hepatocytes plated on coll-coated glass during bile canaliculi formation induced by collagen overlay. Bar 20 μm.

Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organization

David Cohen, Francisco Lázaro-Diéguez, and Anne Müsch

J Cell Sci 2025. 138:None-None; doi: 10.1242/jcs.264412